Home DNA Health Test DNA + Epigenetics Test Nutrition guide LEARN

Your Cart

$0.00

Remove

Subtotal

Pay with browser.

Continue to Checkout

No items found.

Product is not available in this quantity.

Heart Health

Stay In Rhythm

These reports give you the inside scoop on your genetic predisposition to heart conditions like high blood pressure, high cholesterol, and irregular heart rate. With this info, you can take charge of your heart health and make targeted lifestyle changes or seek medical care to keep your ticker ticking strong.

‍

Cardiovascular Health Issues

Cholesterol LDL/HDL Imbalance

Salt Causing High Blood Pressure

Genetic High Blood Pressure

Irregular Heart Rate

Reports

Cardiovascular Health Issues

Genes of Interest: CDKN2A, CDKN2B, CDKN2BAS, R451Q, MTHFD1L, APOE, SEZ6L, MIA3, CXCL12, SMAD3

Genetics play a significant role in determining our overall health and well-being, including our cardiovascular health. There are several genes that have been linked to an increased risk of cardiovascular health issues, including CDKN2A, CDKN2B, CDKN2BAS, R451Q, MTHFD1L, APOE, SEZ6L, MIA3, CXCL12, and SMAD3.

CDKN2A and CDKN2B are both genes that play a role in regulating cell cycle progression and apoptosis. Mutations in these genes have been linked to an increased risk of developing cardiovascular disease. CDKN2BAS is a gene that regulates cell proliferation and has also been linked to an increased risk of cardiovascular disease.

R451Q is a variant in the MTHFD1L gene, which plays a role in regulating the metabolism of folate and other B vitamins. This variant has been linked to an increased risk of developing cardiovascular disease.

APOE is a gene that produces a protein involved in cholesterol metabolism. Variants of this gene have been associated with an increased risk of developing cardiovascular disease, as well as Alzheimer's disease.

SEZ6L is a gene involved in synaptic function and has been linked to an increased risk of cardiovascular disease, as well as other health conditions such as depression and schizophrenia.

MIA3 is a gene that is involved in regulating the immune system and has been linked to an increased risk of cardiovascular disease. CXCL12 is a gene that plays a role in regulating the migration of immune cells and has also been linked to an increased risk of cardiovascular disease.

SMAD3 is a gene involved in the regulation of the TGF-β signaling pathway, which is involved in the development of cardiovascular disease. Mutations in this gene have been linked to an increased risk of developing cardiovascular disease.

In conclusion, these genes play a critical role in determining our risk of developing cardiovascular disease. It is important to understand our genetic makeup and to make lifestyle changes to reduce our risk of developing these health conditions. Regular check-ups and monitoring of our cardiovascular health can help to prevent or manage any issues that may arise.

Cholesterol LDL/HDL Imbalance

Genes of Interest: ABCG8, PLTP, NUTF2

The genes ABCG8, PLTP, and NUTF2 can have an impact on cholesterol levels in the body. Studies have shown that variations in these genes can affect the balance between low-density lipoprotein (LDL) cholesterol, commonly referred to as "bad" cholesterol, and high-density lipoprotein (HDL) cholesterol, commonly referred to as "good" cholesterol.

ABCG8 is a gene that is involved in the regulation of cholesterol and lipid metabolism. Studies have shown that variations in this gene can impact the levels of cholesterol in the blood and contribute to an imbalance between LDL and HDL cholesterol.

PLTP is a gene that is involved in the transportation and metabolism of lipoproteins, including cholesterol. Variations in this gene have been linked to increased levels of LDL cholesterol and decreased levels of HDL cholesterol, leading to an imbalance in the cholesterol levels.

NUTF2 is a gene that is involved in the regulation of lipid metabolism and cholesterol levels. Studies have shown that variations in this gene can affect the balance between LDL and HDL cholesterol and contribute to an imbalance in the cholesterol levels.

By understanding the genetic basis of cholesterol imbalances, individuals can gain insight into their tendencies and take steps to maintain healthy cholesterol levels.

Genetic High Blood Pressure

Genes of Interest: CPLX3, PPARGC1A, APOA5, ADRB2, ADD1, MTHFR

High blood pressure is a common health condition that affects a large portion of the population. It is a major risk factor for heart disease and stroke. While lifestyle factors such as diet and exercise play a big role in regulating blood pressure, genetics can also play a part. Studies have found that several genes are associated with high blood pressure.

CPLX3: The gene CPLX3 is involved in the regulation of blood pressure. Mutations in this gene have been linked to increased risk of high blood pressure.

PPARGC1A: This gene is involved in regulating glucose and fat metabolism, and has been linked to high blood pressure in some studies.

APOA5: This gene is involved in the regulation of lipid metabolism, and variations in this gene have been associated with increased risk of high blood pressure and cardiovascular disease.

ADRB2: This gene plays a role in regulating blood pressure and heart rate, and variations in this gene have been linked to increased risk of high blood pressure.

ADD1: This gene is involved in the regulation of blood vessels, and mutations in this gene have been linked to high blood pressure.

MTHFR: This gene plays a role in the metabolism of folic acid, and variations in this gene have been associated with increased risk of high blood pressure and cardiovascular disease.

Irregular Heart Rate

Genes of Interest: MIR297, PITX2, GRK5

Genetics can play a role in our heart health and heart rate regulation, and certain genes have been found to be associated with an increased risk of irregular heart rate.

MIR297, for example, has been linked to heart rate regulation and the development of heart rhythm disorders. In a study published in the Journal of the American Heart Association, researchers found that variations in the MIR297 gene were associated with an increased risk of atrial fibrillation, a type of irregular heart rate.

The PITX2 gene, which is involved in the development of the heart and cardiovascular system, has also been linked to heart rate regulation and the risk of irregular heart rate. In a study published in the journal Heart Rhythm, researchers found that variations in the PITX2 gene were associated with an increased risk of atrial fibrillation.

The GRK5 gene has also been implicated in heart rate regulation and the risk of irregular heart rate. In a study published in the journal Circulation, researchers found that variations in the GRK5 gene were associated with an increased risk of atrial fibrillation and ventricular arrhythmias, which are conditions characterized by an irregular heart rate.

Salt Causing High Blood Pressure

Genes of Interest: ADD1

Salt sensitivity is a major risk factor for high blood pressure and cardiovascular disease. Some individuals may be more susceptible to the effects of salt on blood pressure due to their genetic makeup. The gene ADD1 has been linked to salt sensitivity and high blood pressure.

Studies have shown that individuals with variations in the ADD1 gene are more sensitive to the effects of salt on blood pressure. This means that they may experience a greater increase in blood pressure in response to a high-salt diet compared to individuals with different variations of the gene.

Additionally, research has indicated that individuals with the ADD1 gene variant may benefit from a low-salt diet in terms of reducing blood pressure and reducing their risk for cardiovascular disease.

It's important to note that genetics is just one aspect of the development of high blood pressure and salt sensitivity. Other factors such as lifestyle habits, diet, and overall health also play a role.

Back to Reports

Our Products

DNA Health Test

£99.00

Understand how your genes could be affecting your health with over 100 health insights, and gain access to a personalised meal and fitness plan designed to push you forward towards your goals.

LEARN MORE

DNA + Epigenetics Test

£199.00

Our most comprehensive test, includes all insights from our DNA Health Test + Discover & lower your biological age in multiple areas and track how your lifestyle may be affecting your genes.

LEARN MORE